Philipp Knechtle Selected Research

Cefepime (Maxipime)

1/2021	Sigmoid Emax Modeling To Define the Fixed Concentration of Enmetazobactam for MIC Testing in Combination with Cefepime.
12/2020	Intrapulmonary Pharmacokinetics of Cefepime and Enmetazobactam in Healthy Volunteers: Towards New Treatments for Nosocomial Pneumonia.
1/2020	Pharmacokinetics-Pharmacodynamics of Enmetazobactam Combined with Cefepime in a Neutropenic Murine Thigh Infection Model.
1/2020	Pharmacodynamics of Cefepime Combined with the Novel Extended-Spectrum-β-Lactamase (ESBL) Inhibitor Enmetazobactam for Murine Pneumonia Caused by ESBL-Producing Klebsiella pneumoniae.
1/2019	Development of Broth Microdilution MIC and Disk Diffusion Antimicrobial Susceptibility Test Quality Control Ranges for the Combination of Cefepime and the Novel β-Lactamase Inhibitor Enmetazobactam.
1/2019	In Vitro Activity of Cefepime-Enmetazobactam against Gram-Negative Isolates Collected from U.S. and European Hospitals during 2014-2015.

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Philipp Knechtle Research Topics

Disease

4	Infections 01/2021 - 01/2019
3	Urinary Tract Infections (Urinary Tract Infection) 01/2020 - 01/2019
2	Healthcare-Associated Pneumonia 12/2020 - 01/2020
1	Cross Infection (Nosocomial Infection) 12/2020
1	Body Weight (Weight, Body) 01/2020
1	Pneumonia (Pneumonitis) 01/2020
1	Pyelonephritis 01/2020
1	Tinea (Ringworm) 01/2014
1	Trichophyton infection 01/2014

Drug/Important Bio-Agent (IBA)

6	enmetazobactamIBA 01/2021 - 01/2019
6	Cefepime (Maxipime)FDA LinkGeneric 01/2021 - 01/2019
2	Carbapenems (Carbapenem Antibiotics)IBA 01/2021 - 01/2019
1	LactamsIBA 12/2020
1	beta-Lactamase InhibitorsIBA 01/2020
1	Tazobactam FDA LinkGeneric 01/2019
1	furanIBA 01/2014
1	Fatty Acids (Saturated Fatty Acids)IBA 01/2014